Scientific Program

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    Keynote Speaker: 
    Shinya Yamanaka, M.D., Ph.D.
    2012 Nobel Laureate in Medicine
    Director, Center for iPS Cell Research and Application (CiRA) 
    Kyoto University


    Speaker List and Topics

    Symposium 1: Osteoporosis: anabolic agents
    Chairs: Toshiyuki Yoneda, Jack Martin 

    Targeting sclerostin in the development of therapeutics for bone disorders
    David Ke (Amgen, Inc., USA) 

    Eldecalcitol for osteoporosis
    Toshio Matsumoto (The University of Tokushima, Japan) 

    Potential therapeutic targets for age-related bone loss
    Sundeep Khosla (Mayo Clinic, USA) 

    Symposium 2: Osteoporosis: anti-resorptive agents
    Chairs: Takashi Nakamura, Ian Reid  

    Japanese experiences in the use of bisphosphonates
    Hiroshi Hagino (Tottori University, Japan) 

    Denosumab for osteoporosis
    Richard Eastell (The University of Sheffield, UK) 

    Odanacatib treatment for osteoporosis
    Henry Bone (Michigan Bone and Mineral Clinic, USA) 

    Symposium 3: Osteoporosis: pathophysiology and epidemiology
    Chairs: Toshitsugu Sugimoto, Roger Bouillon 

    Advanced glycation end-products (AGEs) on the risk of fracture in older patients with osteoporosis
    Toshitaka Nakamura (University of Occupational and Environmental Health, Japan)

     Glucocorticoid-induced osteoporosis
    Juliet Compston (University of Cambridge, UK)

     Pathogenesis and treatment of patients with low BMD
    Seiji Fukumoto (The University of Tokyo Hospital, Japan)

    Symposium 4: Cancer and bone: basic, translational, and clinical
    Chairs: Yoshiya Tanaka, Theresa Guise 

    Epithelial-mesenchymal transition of breast cancer in bone
    Toshiyuki Yoneda (Indiana University, USA/ Osaka University, Japan)

    Constituents of the hematopoietic stem cell niche
    Paul Frenette (Albert Einstein College of Medicine, USA)

    Cancer and bone: basic, translational and clinical.
    Robert Coleman (The University of Sheffield, UK)

    Symposium 5: Muscle and bone
    Chairs: Masaaki Inaba, Chris Kovacs  

    Effects of aging on muscle and bone
    Steve Cummings (University of California, San Francisco, USA)

    Osteoporosis in men 
    Eric Orwoll (Oregon Health and Science University, USA)

    Towards the elucidation of androgen signaling in skeletal muscles
    Daniel Metzger (Institute of Genetics and Molecular and Cellular Biology (IGBMC), France)

    Symposium 6: Tissue Engineering
    Hideki Yoshikawa, Henry Kronenberg  

    Chondrocyte differentiation and direct conversion to chondrogenic cells
    Noriyuki Tsumaki (Kyoto University, Japan)

    Coordinated regulation of bone remodeling and fat formation by the Zinc Finger Protein 521 and its interactions with Ebf1
    Roland Baron (Harvard Medical School and Harvard School of Dental Medicine, USA)

    Stem cell populations and signals that regulate bone regeneration
    Regis O'Keefe (The University of Rochester Medical Center, USA)

    Symposium 7: Osteoctye
    Chairs: Naoyuki Takahashi, Stavros Manolagas  

    The material and structural basis of the earlier gain and later loss of bone’s material and structural strengths
    Ego Seeman (The University of Melbourne, Australia)

    Osteocytes acting like osteoclasts and osteoblasts
    Lynda Bonewald (University of Missouri-Kansas City, USA)

    Osteocytes and bone resorption
    Hiroshi Takayanagi (The University of Tokyo, Japan)


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